cees dekker Things To Know Before You Buy

cees dekker Things To Know Before You Buy

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Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules

Around the same time, the team of Paul McEuen, who was then based mostly in the College of California, Berkeley, showed comparable success on ropes of bundled nanotubes. Depending upon the wrapping angle, nanotubes can can be found in metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed working with scanning tunnelling spectroscopy experiments.

Non-equilibrium folding of particular person DNA molecules recaptured up to a thousand periods inside of a solid state nanopore

2010, made a brand new way (‘wedging transfer’) to control nanostructures; 1st report of DNA translocation as a result of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into solid-state nanopores

Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

Many associated developments followed, exactly where our group proven diverse transistor variants for instance one-electron transistors at place temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into compact evidence-of-basic principle Digital circuits.

Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim from the pore is highlighted in crimson, and a 3D rendering with the motion of your DNA rod is displayed.

‘Certainly, I realize people today had been amazed at the time. At the end of the nineties, After i was in my forties, I was Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t study A lot any more. The sphere went much more into the appliance facet, how you can integrate nanotubes into Digital circuits.

There was 1 difficulty however — we didn't notice any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule amount, conducting polymers were being basically not this kind of fantastic conductors, which was fairly disappointing. We As a result broadened our look at to test to seek out additional promising molecules.

An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes

‘That problems the synthetic cell, as Element of the Dutch BaSyC initiative. Craig Venter looked top rated-down in those days and discovered about five hundred genes which might be minimally demanded for any performing mobile. We want to seem base-up: how can we transfer from the couple molecules to a complete biological process?

Visualization of unstained DNA nanostructures with Superior in-concentration transmission electron microscopy procedures

Good-point out nanopores have tested to generally be a shockingly multipurpose probe for one-molecule Assessment of DNA. https://www.ceesdekker.net I'll explain a number of our the latest conclusions – specially DNA knots – together with our initiatives to develop the abilities of sound-state nanopores even additional, within the direction of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.